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I had many guinea pigs. And as the previous people stated, you should NOT put them in exercise balls. And if you have wheels, you need one specially designed for guinea pigs. Hamster wheels are much too small for guinea pigs, and the strain will hurt their backs. If your guinea pigs are anything like the 10 I have, they don't use the wheels anyway. My husband's a vet that specializes in small and exotic animals, so yes, I do know what I'm talking about.